CBDD Group

1. 个人基本情况：

董界 

2008-2012 中南大学药学院， 学士

2012-2014 中南大学药学院，硕士

2014-2017.11 中南大学药学院，博士

2018.03-今 中南林业科技大学，讲师

2019.05-今 澳门大学，博士后

邮箱：biomed@csu.edu.cn

2. 研究方向

●  基于人工智能系统和系统药理学的计算机辅助分子设计研究；
● 系统生物学和药物发现过程中软件、Web服务及数据库的开发；
● 食品科学中数据库、工具开发，以及基于结构的虚拟筛选方法的开发.；

3. 代表性论文：

• Dong J, Zhu, M. F., Yun, Y. H., Lu, A. P., Hou, T. J., & Cao, D. S., BioMedR: an R/CRAN package for integrated data analysis pipeline in biomedical study. Briefings in Bioinformatics. 2019.(JCR一区，IF：9.101)
• Dong J, Yao Z J, Zhang L, et al. PyBioMed: a python library for various molecular representations of chemicals, proteins and DNAs and their interactions [J]. Journal of Cheminformatics, 2018, 10(1): 16. (JCR一区，IF：4.22)
  
• Dong J, Wang N N, Yao Z J, et al. ADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database[J]. Journal of Cheminformatics, 2018, 10(1): 29.  (JCR一区，IF：4.22)
• Wang N N#, Dong J#, Zhang L, et al. HAMdb: a database of human autophagy modulators with specific pathway and disease information[J]. Journal of Cheminformatics, 2018, 10(1): 34. (JCR一区，IF：4.22)
  
• Dong J, Cao D S, Miao H Y, et al. ChemDes: an integrated web-based platform for molecular descriptor and fingerprint computation[J].Journal of Cheminformatics, 2015, 7(1): 1-10. (JCR一区，IF：4.22)
• Dong J, Yao Z J, Wen M, et al. BioTriangle: a web-accessible platform for generating various molecular representations for chemicals, proteins, DNAs/RNAs and their interactions[J]. Journal of Cheminformatics, 2016, 8(1): 1-13. (JCR一区，IF：4.22)
• Dong J, Yao Z J, Zhu M F, et al. ChemSAR: an online pipelining platform for molecular SAR modeling[J]. Journal of Cheminformatics, 2017, 9(1): 1-13. (JCR一区，IF：4.22)
• [4] Dong J, Wang N N, Liu K Y, et al. ChemBCPP: A freely available web server for calculating commonly used physicochemical properties[J]. Chemometrics and Intelligent Laboratory Systems, 2017, 171: 65-73(JCR一区，IF：2.22)
• [5] Wang N N*, Dong J, Deng Y H, et al. ADME properties evaluation in drug discovery: prediction of Caco-2 Cell permeability using a combination of NSGA-II and boosting[J].Journal of Chemical Information and Modeling, 2016, 56(4): 763-773. (JCR一区，IF：3.76)
• [6] Yao Z J*, Dong J*, Che Y J, et al. TargetNet: a web service for predicting potential drug-target interaction profiling via multi-target SAR models[J].Journal of Computer-Aided Molecular Design, 2016, 30(5): 413-424.(JCR一区，IF：3.02)
• [7] Dong J, Liu S, Zhu X L, et al. Ti-AI intermetallic compound membrane refining Chinese medicinal materials extract[J]. Journal of Chinese Medicinal Materials, 2014, 37(9): 1673-1675. (CSCD核心期刊)
• Cao D S, Dong J, Wang N N, et al. In silico toxicity prediction of chemicals from EPA toxicity database by kernel fusion-based support vector machines[J]. Chemometrics and Intelligent Laboratory Systems, 2015, 146: 494-502. (JCR一区，IF：2.22)
• Wang N N, Huang C, Dong J, et al. Predicting human intestinal absorption with modified random forest approach: a comprehensive evaluation of molecular representation, unbalanced data, and applicability domain issues[J]. RSC Advances, 2017, 7(31): 19007-19018. (JCR二区，IF：3.10)
• Gao T, Cao X, Dong J, et al. A novel water soluble multifunctional fluorescent probe for highly sensitive and ultrafast detection of anionic surfactants and wash free imaging of Gram-positive bacteria strains[J]. Dyes and Pigments, 2017, 143: 436-443. (JCR一区，IF：3.47)
• Yang S, Gao T, Dong J, et al. A novel water-soluble AIE-based fluorescence probe with red emission for the sensitive detection of heparin in aqueous solution and human serum samples[J].Tetrahedron Letters, 2017, 58(37): 3681-3686. (JCR二区，IF：2.19)
• Wang N N, Deng Z K, Huang C, Dong J, et al. ADME properties evaluation in drug discovery: Prediction of plasma protein binding using NSGA-II combining PLS and consensus modeling[J].Chemometrics and Intelligent Laboratory Systems, 2017, 170: 84-95. (JCR二区，IF：2.22)
• Wang Y, Huang J J, Zhou N, Dong J, et al. Incorporating PLS model information into particle swarm optimization for descriptor selection in QSAR/QSPR[J]. Journal of Chemometrics, 2015, 29(12): 627-636. (JCR二区，IF：1.87)
• Gao T, Cao X, Ge P, Dong J, et al. A self-assembled fluorescent organic nanoprobe and its application for sulfite detection in food samples and living systems[J].Organic & Biomolecular Chemistry, 2017, 15(20): 4375-4382. (JCR一区，IF：3.56)
• Cao D S, Deng Z K, Zhu M F, Dong J, et al. Ensemble partial least squares regression for descriptor selection, outlier detection, applicability domain assessment, and ensemble modeling in QSAR/QSPR modeling[J]. Journal of Chemometrics, 2017, 31(11): e2922. (JCR二区，IF：1.88)
• Gao T, Yang S, Cao X, Dong J, et al. Smart self-assembled organic nanoprobe for protein-specific detection: design, synthesis, application, and mechanism studies[J]. Analytical Chemistry, 2017, 89(18): 10085-10093. (JCR一区，IF：6.32)
• Bi A, Gao T, Cao X, Dong J, et al. A novel naphthalimide-based probe for ultrafast, highly selective and sensitive detection of formaldehyde[J]. Sensors and Actuators B: Chemical, 2018, 255(3): 3292-3297. (JCR一区，IF：5.40)

4. 获得荣誉

● 2019年度中南大学优秀博士学位论文；

● 2016年度拔尖博士生校长奖学金一等奖；

● 2016年度中南大学“ 十佳”优秀博士；

● 2016年度研究生国家奖学金；

● 2017年度中南大学卢惠霖奖励金；

● 2015年度中南大学卢惠霖奖励金；

● 中南大学药学院2013-2015年度“ 优秀共产党员”；

5. 代表成果

6. 联系方式

Google scholar: https://scholar.google.com/citations?user=phFGEecAAAAJ&hl=zh-CN

Homepage: http://www.dj-science.org; http://www.scbdd.com.